What Are The Symptoms Of Multiple System Atrophy: All You Need To Know

Feb 08, 2025 By Alison Perry

The rare and progressive neurological condition known as Multiple System Atrophy (MSA) compromises motor control and the autonomic nervous system. MSA symptoms differ from person to person and usually start gently before developing to more severe disabilities. MSA can be difficult to identify since it might replicate other disorders, including Parkinson's disease.

Early recognition of the symptoms can help to improve management. This article explores the typical symptoms of multiple system atrophy, clarifying how this disorder affects the body and what you should expect. Let's discuss the main symptoms of MSA, from mobility problems to autonomic dysfunction.

Early Signs of Multiple System Atrophy:

Often modest, early signs of multiple system atrophy may be mistaken for other medical disorders. Typical early symptoms are trouble with coordination, walking, and balance. Many persons with MSA feel as though their muscles are stiff or tight. That resembles Parkinson's disease except in the underlying causes and course of advancement. Certain people can also find their handwriting changed or their speech shaky. Though there is no cure for MSA, early discovery is essential since it helps start the therapy process sooner. Early symptom recognition will enable doctors to identify the condition.

People with MSA may also have trouble controlling their bladder and regulating blood pressure, two autonomic skills. The condition worsens these problems as it advances. For instance, a rapid drop in blood pressure could cause orthostatic hypotension, or vertigo, when standing. That is a major clue that differentiates MSA from other neurological disorders.

Movement Problems in Multiple System Atrophy

Movement issues are becoming more noticeable as MSA advances. A primary MSA sign is the slow loss of motor control. That shows up as muscle rigidity, bradykinesia—slowness of movement—and tremors, which seriously affect daily tasks. MSA's motor symptoms can cause trouble with simple tasks such as eating, dressing, and walking. MSA is distinguished in many ways by a disorder known as "parkinsonism." This name describes symptoms including slow motions, stiffness, and tremors akin to Parkinson's disease.

Nevertheless, unlike Parkinson's disease, MSA's tremors are less frequent and usually affect the trunk or limbs. Apart from the motor issues, persons with MSA also frequently suffer from fine motor skills. Tying shoes or buttoning a blouse, for instance, gets more challenging. Many people also mention problems with posture, usually leaning either forward or backward, which could lead to falls and injuries.

Autonomic Dysfunction Symptoms of MSA

One of the toughest features of multiple system atrophy is autonomic dysfunction. Heart rate, blood pressure, digestion, and temperature control are among the autonomic nervous systems that control involuntary body activities. Various alarming symptoms follow a dysfunction of this system brought on by MSA. Properly controlling blood pressure is among the most common autonomic symptoms. MSA can induce orthostatic hypotension, a disorder in which blood pressure drops dramatically when standing, causing dizziness and fainting, as was noted before.

Common in those with MSA are also bladder control issues. Many people suffer from frequent urinating urges or urine incontinence, which can interfere with daily activities and quality of life. Eating and drinking might also be difficult if dysphagia, or difficulty swallowing, strikes you. The compromised autonomic function that defines MSA causes these symptoms.

Speech and Swallowing Difficulties in MSA

Among the major symptoms of multiple system atrophy are speech and swallowing difficulties, which can make eating and speaking challenging. Many with MSA have dysarthria, a disorder causing slurred or delayed speech. This can influence one's ability to interact with people, causing isolation and dissatisfaction. Apart from speech impairments, MSA sufferers often have swallowing challenges.

Often referred to as dysphagia, this condition can cause aspiration—food or liquid getting into the windpipe—or choking. People with MSA could find it difficult to swallow solid foods and liquids, which could be especially challenging. These speech and swallowing difficulties are increasingly severe as the illness advances. To help handle these difficulties, some persons might need speech therapy or feeding tubes.

Cognitive and Mood Changes in Multiple System Atrophy

MSA can influence cognitive skills and emotions even though it mostly influences mobility and autonomic processes. Some persons with MSA experience minor cognitive impairment or trouble focusing and remembering. Though less noticeable than in disorders like Alzheimer's dementia, these alterations can nonetheless be disturbing.

For those with MSA, another issue is mood fluctuations. Those with the condition are rather prone to anxiety and depression. These disorders can be exacerbated by the emotional toll of coping with MSA symptoms as well as by the aggravation of losing autonomy. Those with MSA and their caregivers should ask mental health specialists for help as needed.

Diagnosis and Testing for Multiple System Atrophy

Because its symptoms cross those of other diseases, including Parkinson's disease and other neurodegenerative diseases, diagnosing multiple system atrophy can be challenging. Since no one test exists to validate the diagnosis, doctors use a mix of clinical assessment, medical history, and diagnostics to exclude other disorders.

MRI scans and other neuroimaging methods can give important new perspectives on the state of the brain and assist with MSA detection using alterations. Other procedures to evaluate the degree of autonomic dysfunction could include autonomic function tests. Sometimes, a definite diagnosis can take months or even years as the condition advances.

Managing the Symptoms of MSA

While multiple system atrophy cannot be cured, numerous treatments can help control symptoms and enhance quality of life. Medications are often recommended to treat particular symptoms, including urine problems, blood pressure concerns, and muscular tension. Certain drugs enhance blood pressure control, therefore helping to control orthostatic hypotension.

Controlling MSA includes occupational treatment, speech therapy, and physical therapy. These treatments enable people to keep mobility, enhance communication, and adjust to everyday chores. Additionally, they advised simplifying everyday life with adaptive tools, including walking assistance or customized utensils.

Conclusion:

Multiple system atrophy is ultimately a complicated and progressive neurological condition with a spectrum of symptoms. These cover mobility challenges, autonomic dyspnea, speech difficulties, and mood swings. Managing symptoms and improving quality of life depends on early diagnosis and treatment. Although MSA has no cure, treatments and medicines can help reduce the symptoms and assist people in leading healthier lives. See a doctor for evaluation and treatment if you or someone you know has these symptoms.